Neurophysiology
Teaching hours and weekly schedule
This is a 1st semester elective course of about 2,5 weeks that corresponds to 5 ECTs and 39 total hours of lectures including student presentations..
Co-ordinators
- Irene Skaliora, Professor of Neuroscience and Cognitive Science, Department of History and Philosophy of Science, National & Kapodistrian University of Athens and Biomedical Research Foundation of the Academy of Athens.
- Christos Consoulas, Associate Professor of Experimental Physiology, Laboratory of Physiology, Medical School of Athens, National & Kapodistrian University of Athens.
Description:
This 2,5-week course will focus on cellular and molecular neuroscience. It will cover the mechanisms that operate to regulate neuronal excitability, dendritic and synaptic function; plasticity and neural circuits. This is an intensive course focused on cellular neurophysiology. The main aim of the course is to understand the principles of signal generation, modulation and transmission, both at the cell and circuit level.
Learning Resource
Kandel ER, Schwartz JH, Jessell, TM, et al. Principles of Neural Science 5th Edition (2012). McGraw-Hill NY. ISBN 0071390111
Course Overview
- Introduction lecture
- Ion channels
- Membrane potential, Nernst Equation, Goldman Equation
- Electrotonic potential
- Passive membrane properties
- Action potential
- Na+, K+, and Ca++ channels and currents
- Mechanisms of pre-synaptic release
- Synaptic transmission - ligand gated and G-protein synaptic transmission
- Neuromuscular Junction
- CNS synaptic transmission 1- excitation Glutamatergic
- CNS synaptic transmission 2- inhibition - GABAergic and Glycinergic
- CNS synaptic transmission 3- synaptic integration.
- Neural Circuits: methods of recording and analysis
- Modulation of Neural Circuits
Titles of lectures and names of the lecturers
A/A | Neurophysiology | Lecturer |
1 | Cellular excitability, capacitance, input resistance, resting and action potentials, cable theory, voltage clamp | Christos Consoulas |
2 | NMJ & Quantal Release | Christos Consoulas |
3 | Central Synapses: Excitatory and inhibitory, short and long term plasticity, paired pulse facilitation & depression, LTP/LTD | Irene Skaliora |
4 | Neurophysiology of brain networks: methods of recording and analysis | Irene Skaliora |
5 | Calcium channels in synapses | Carsten Duch |
6 |
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7 |
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